Designing pharmacokinetic studies for long-acting veterinary drugs comes with unique pitfalls—especially when flip-flop kinetics are involved. In this session from the Certara Customer Education Series, experts break down how slow-release formulations can shift the terminal phase of a PK profile, why this matters for bioavailability and half-life interpretation, and how to avoid common design mistakes. Through clear examples, simulations, and practical recommendations, the webinar highlights how thoughtful sampling strategies and early pilot work can prevent costly misinterpretations and support sound regulatory decisions.